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Phenethylamine Basics

We talked tryptamines and ergolines, but what about the third structural classification of psychedelics - phenethylamines?


Phenethylamines are named after their chemical structure which shares a strong resemblance to that of dopamine. Despite this difference in structure from the tryptamines, it still activates serotonin receptors (sometimes with more affinity than the ones that look like serotonin!)


The similarity of phenethylamines with the endogenous monoamine compound, dopamine, can be seen below and talked about in more detail here. They all share the phenyl ring, which are modified to produce different compounds. This also includes non-psychoactive compounds and psychostimulants like amphetamine.




See our video below in how these phenethylamines share some structural features but differ in others:





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